The Computational Structural Bioinformatics Workshop (CSBW 2025), which aims to foster collaboration among experts from computer science, artificial intelligence, statistics, biology, and medicine, will be co-located with ACM BCB 2025 (Philadelphia, PA, USA, October 11-15, 2025). We invite high-quality, original papers and posters addressing computational challenges related to biomolecular structure.This year, in addition to classical techniques, the workshop will emphasize the application of AI in structural biology, including deep learning for structure prediction, generative modeling, protein design, and structural data analysis (e.g., cryo-EM, cryo-ET, NMR, X-ray).

For more information about CSBW 2025, please visit: cs.wwu.edu/csbw

Submission Guidelines

Please submit full papers, up to 6 pages, including references, formatted according to the double-column ACM SIG conference style. We will follow a single-blind review process. At least 2 committee members will review each submission, and acceptance decisions will be made using EasyChair's scoring and confidence review capabilities.

All papers must be original and not simultaneously submitted to another journal or conference. All paper should be submitted to Easychair:  https://easychair.org/conferences?conf=csbw2025

Authors of accepted papers will be given the opportunity to give a 20-minute oral summary of their work, followed by a Q&A session. At least one author of an accepted paper is required to register for the workshop to have the manuscript appear in the proceedings.

Important Dates

• 22 August 2025: Full paper submission deadline
• 3 September 2025: Notification of acceptance sent to authors
• 8 September 2025: Camera-ready submission deadline
• 11 October 2025: Workshop date

List of Topics

Topics of interest, but not limited to, include the following:

• Structure representation
• Structure prediction
• Structure alignment
• Interaction and docking
• Molecular dynamic simulations
• Biomolecular graphics
• Coarse-grained modeling
• Data mining of structural data
• Structural genomics, and optimization in structural problems
• High performance computing in modeling
• Graph theory applied to structural problems
• Bio-molecular structure refinement
• Structure-based drug design
• Applications of AI in structural biology, such as deep learning for structure prediction, generative modeling, protein design, and structural data analysis (e.g., cryo-EM, NMR, X-ray)

Committees

Program Committee

• Amarda Shehu, Department of Computer Science, George Mason University
• Brian Chen, Department of Computer Science and Engineering, Lehigh University
• Bruna Jacobson, Department of Computer Science, University of New Mexico
• Fardina Fathmiul Alam, Department of Computer Science, University at Maryland, College Park
• Filip Jagodzinski, Department of Computer Science, Western Washington University
• Gideon Gogovi, Department of Biostatistics and Health Data Science, Lehigh University
• Jin Chen, Department of Medicine, University of Alabama at Birmingham
• Jianlin Cheng, Department of Electrical Engineering and Computer Science, University of Missouri
• Jing He, Department of Computer Science, Old Dominion University
• Kamal Al Nasr, Department of Computer Science, Tennessee State University
• Kevin Molloy, Department of Computer Science, James Madison University
• Kazi Lutful Kabir, Department of Information Sciences and Technology, George Mason University
• Nasrin Akhter, Department of Computer Science and Engineering, University at Buffalo (UB)
• Negin Forouzesh, Department of Computer Science, California State University- Los Angeles

Steering Committee

• Jing He, Dept. of Computer Science, Old Dominion University
• Brian Chen, Computer Science and Engineering, Lehigh University
• Willy Wriggers, Old Dominion University
• Vasant Honavar, Biomedical Data Science, Pennsylvania State University
• Nurit Haspel, Dept. of Computer Science, UMass Boston
• Lydia Kavraki, Dept. of Computer Science, Rice University
• Anna Panchenko, Biomedical and Molecular Sciences, Queen's University, Canada
• Amarda Shehu, Dept. of Computer Science, George Mason University
• Yaoqi Zhou, School of Informatics, Indiana University-Purdue University Indianapolis

Organizing Committee and Program Co-Chairs

• Salim Sazzed, Georgia Sothern University, ssazzed@georgiasouthern.edu
• Brian Chen, Lehigh University, byc210@lehigh.edu

Publication

Accepted papers for CSBW will be formally published in a peer-reviewed proceedings alongside those of ACM-BCB. To encourage submissions and foster increased interest, we are also currently in discussions with several journal editors to solicit a special issue for CSBW 2025. In past CSBWs, special issue submissions have appeared in Bioinformatics Advances, Biomolecules, Molecules, Journal of Computational Biology, and BMC Structural Biology.

Venue

The Computational Structural Bioinformatics Workshop (CSBW 2025) will be co-located with ACM BCB 2025 in Philadelphia, PA, USA, on October 11, 2025.

Contact

All questions about submissions should be emailed to : ssazzed@georgiasouthern.edu or byc210@lehigh.edu.